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Aldactone (spironolactone) is an aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium.Medscape - Hypertension, congestive heart failure, hyperaldosteronism-specific dosing for Aldactone (spironolactone), frequency-based adverse effects, comprehensive.

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The effect of food on spironolactone absorption (two 100 mg ALDACTONE tablets) was assessed in a single-dose study of 9 healthy, drug-free volunteers.

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